Salvia macilenta exhibits antiglycating activity and protects PC12 cells against H2O2-induced apoptosis
نویسندگان
چکیده
منابع مشابه
Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
Objective(s): Neurodegenerative diseases have been associated with glutamatergic dysfunction. Berberine, an isoquinoline alkaloid broadly present in different medicinal herbs, has been reported to have neuroprotective effect. In the present study, the effects of berberine against glutamate-induced oxidative damage and apoptosis were investigated. Materials and Methods: The cultured PC12 and N2a...
متن کاملAllicin protects against H2O2-induced apoptosis of PC12 cells via the mitochondrial pathway
Allicin is a major bioactive ingredient of garlic and has a broad range of biological activities. Allicin has been reported to protect against cell apoptosis induced by H2O2 in human umbilical vein endothelial cells. The present study evaluated the neuroprotective effect of allicin on the H2O2-induced apoptosis of rat pheochromocytoma PC12 cells in vitro and explored the underlying mechanism in...
متن کاملLong Noncoding RNA MHRT Protects Cardiomyocytes against H2O2-Induced Apoptosis
Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. The exploration of new biomarkers with high sensitivity and specificity for early diagnosis of AMI therefore becomes one of the primary task. In the current study, we aim to detect whether there is any heart specific long noncoding RNA (lncRNA) releasing into the circulation during AMI, and explore i...
متن کاملNimodipine Protects PC12 Cells against Oxygen-Glucose Deprivation
The protective effect of a L-type calcium channel blocker, nimodipine, on cell injury induced by oxygen-glucose deprivation (OGD) in PC12 cells was investigated. PC12 cells were exposed to in-vitro oxygen-glucose deprivation (30 minutes and 60 minutes respectively) in the presence or absence of nimodipine (10mM/L) in three different time schedules (pre-24h, pre-3h and concurrently). Cellular vi...
متن کاملBerberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
OBJECTIVES Neurodegenerative diseases have been associated with glutamatergic dysfunction. Berberine, an isoquinoline alkaloid broadly present in different medicinal herbs, has been reported to have neuroprotective effect. In the present study, the effects of berberine against glutamate-induced oxidative damage and apoptosis were investigated. MATERIALS AND METHODS The cultured PC12 and N2a c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cytotechnology
سال: 2013
ISSN: 0920-9069,1573-0778
DOI: 10.1007/s10616-013-9550-x